|
Mutation Information
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Mutation Site
|
G123E |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Gag |
Literature Information
|
PubMed PMID
|
33425260
|
|
Published Year
|
2021 |
|
Journal
|
Computational and structural biotechnology journal |
|
Title
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The impact of Gag non-cleavage site mutations on HIV-1 viral fitness from integrative modelling and simulations. |
|
Author
|
Samsudin F,Gan SK,Bond PJ |
|
Evidence
|
We found that some mutations, such as G123E and H219Q, involve direct interaction with cleavage site residues to influence their local environment, while certain mutations in the matrix domain lead to the enrichment of lipids important for Gag targeting and assembly.
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HIV Mutation Detail Information