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Mutation Information
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Mutation Site
|
G119T |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Genotype/Subtype
|
A |
Literature Information
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PubMed PMID
|
20881037
|
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Published Year
|
2010 |
|
Journal
|
Journal of virology |
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Title
|
Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site. |
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Author
|
Ito K,Qin Y,Guarnieri M,Garcia T,Kwei K,Mizokami M,Zhang J,Li J,Wands JR,Tong S |
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Evidence
|
The G119E mutant showed much less secreted HBsAg than the G119T and G119V mutants according to the ELISA method but not according to Western blot analysis of HBsAg precipitated by ultracentrifugation.
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HBV Mutation Detail Information