HBV Mutation Detail Information

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Mutation Information
Mutation Site G119E
Mutation Type Amino acid level
Gene/Protein/Region Type S
Literature Information
PubMed PMID 16461214
Published Year 2005
Journal Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title Mechanism of HBV genome variability and replication of HBV mutants.
Author Tong S
Evidence Several core promoter mutants were defective in virion secretion, and mapping experiments revealed three missense mutations in the small envelope protein to be responsible: I110M, G119E, and R169P The effect of I110M and G119E mutations can be relieved by another point mutation that creates a novel N-linked glycosylation site.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation