HBV Mutation Detail Information

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Mutation Information

Mutation Site	G112N
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	A

Literature Information

PubMed PMID	20881037
Published Year	2010
Journal	Journal of virology
Title	Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site.
Author	Ito K,Qin Y,Guarnieri M,Garcia T,Kwei K,Mizokami M,Zhang J,Li J,Wands JR,Tong S
Evidence	Similarly, an artificial G112N mutation creating another novel N-linked glycosylation site (112NST114) could partially rescue the G119E mutant (Fig. 6B and C, lanes 5), although not the I110M or G145R mutant (Fig. (Fig.5B,5B, lanes 3 and 19).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation