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Mutation Information
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Mutation Site
|
G105C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreS |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
21104161
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Frontiers of medicine in China |
|
Title
|
Association of novel mutations and haplotypes in the preS region of hepatitis B virus with hepatocellular carcinoma. |
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Author
|
Xie JX,Zhao J,Yin JH,Zhang Q,Pu R,Lu WY,Zhang HW,Wang HY,Cao GW |
|
Evidence
|
As compared with the HBV-infected subjects without HCC, C2875T, G2946C, A3054C, C3060A, T3066C, C3116T, A3120C, G3191A, A1C, C7A, C10A, A31C, C76T, G105C, and G147C in both genotypes were significantly associated with increased risks of HCC.
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HBV Mutation Detail Information