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Mutation Information
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Mutation Site
|
G105C |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreS |
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Country
|
China |
Literature Information
|
PubMed PMID
|
20419326
|
|
Disease
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HBV infection;
Liver cirrhosis;
Hepatocellular carcinoma
|
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Published Year
|
2010 |
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Journal
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Journal of gastroenterology |
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Title
|
Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma. |
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Author
|
Yin J,Xie J,Zhang H,Shen Q,Han L,Lu W,Han Y,Li C,Ni W,Wang H,Cao G |
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Evidence
|
The HCC-associated mutations C2875A, G2946C, G2950A, G2951A, A2962G, C2964A, A3054C/T, C3060A/T, T3066A/C, T3069G, C3116T, A3120T, G3191A/C, A1C, C7A, C10A, T49A/G, T53C, C76A/T, G105C/T, and G147C generated neither the start nor stop codons.
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HBV Mutation Detail Information