HBV Mutation Detail Information

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Mutation Information

Mutation Site	F97L
Mutation Type	Amino acid level
Gene/Protein/Region Type	C

Literature Information

PubMed PMID	10559327
Published Year	1999
Journal	Journal of virology
Title	Subtype-independent immature secretion and subtype-dependent replication deficiency of a highly frequent, naturally occurring mutation of human hepatitis B virus core antigen.
Author	Yuan TT,Tai PC,Shih C
Evidence	Recently, a phenylalanine (F)-to-leucine (L) mutation at this position (mutant F97L) in HBV surface antigen subtype ayw has been shown to result in an immature secretion phenotype, which is characterized by the nonselective export of an excessive amount of virions containing minus-strand, single-stranded HBV DNA.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation