Mutation Information
Mutation Site
|
F77L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Country
|
Nicaragua |
Literature Information
PubMed PMID
|
27736898
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2016 |
Journal
|
PloS one |
Title
|
HIV Drug Resistance in Antiretroviral Treatment-Naïve Individuals in the Largest Public Hospital in Nicaragua, 2011-2015. |
Author
|
Avila-Ríos S,García-Morales C,Matías-Florentino M,Tapia-Trejo D,Hernández-Álvarez BF,Moreira-López SE,Quant-Durán CJ,Porras-Cortés G,Reyes-Terán G |
Evidence
|
Similarly, within NRTI SDRMs, K70ER, V75A, F77L, M184I, T215I, and K219E were only found under the 5% threshold, while D67G and M184V, although present in levels >=5% in some patients, were also mostly present as low-abundance variants <5% (0.8% vs. 4.7% and 0.8% vs. 3.1%;>=5% vs. <5% respectively).
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