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Mutation Information
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Mutation Site
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F77A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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RT |
Literature Information
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PubMed PMID
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31548705
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Published Year
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2019 |
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Journal
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Nature methods |
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Title
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Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. |
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Author
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Zhou H,Rauch S,Dai Q,Cui X,Zhang Z,Nachtergaele S,Sepich C,He C,Dickinson BC |
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Evidence
|
In the third round (Libraries 14-17), we also screened sites L74, V75, F77, E79 and L80 surrounding 76 and 78 (Supplementary Table 2). RT-973 (V75F/F77A) yielded further improvements in fluorescence signal (Fig. 2c).
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HIV Mutation Detail Information