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Mutation Information
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Mutation Site
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F68D |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vif |
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Combined Mutation
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vif.F68D+vif.I55A;vif.F68D+vif.I55D |
Literature Information
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PubMed PMID
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28302150
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Published Year
|
2017 |
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Journal
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Retrovirology |
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Title
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Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function. |
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Author
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Desimmie BA,Smith JL,Matsuo H,Hu WS,Pathak VK |
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Evidence
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In addition to the F68D mutant, we generated CBFβ mutants I55A, I55D, F68A, I55A–F68D, and I55D–F68D and examined their ability to interact with Vif (Fig. 6).
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HIV Mutation Detail Information