Mutation Information
Mutation Site
|
F61A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Viral Reference
|
K03455.1
|
Literature Information
PubMed PMID
|
16723431
|
Published Year
|
2006 |
Journal
|
Nucleic acids research |
Title
|
Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function. |
Author
|
Mandal D,Dash C,Le Grice SF,Prasad VR |
Evidence
|
Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H functionWe reported previously that substitutions F61L, F61W, F61Y and F61A in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase affect strand displacement synthesis [T.
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