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Mutation Information
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Mutation Site
|
F605A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BRLF1 |
Literature Information
|
PubMed PMID
|
19232420
|
|
Published Year
|
2009 |
|
Journal
|
Virology |
|
Title
|
Two phenylalanines in the C-terminus of Epstein-Barr virus Rta protein reciprocally modulate its DNA binding and transactivation function. |
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Author
|
Chen LW,Raghavan V,Chang PJ,Shedd D,Heston L,Delecluse HJ,Miller G |
|
Evidence
|
The Rta (F600A/F605A) mutant was markedly impaired at activating BLRF2, both in the absence and presence of Z(S186A) (lane 3 and lane 7).
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EBV Mutation Detail Information