Mutation Information
Mutation Site
|
F57V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E7 |
Amino acid_Mutation
|
T732C |
Genotype/Subtype
|
HPV16 |
Country
|
India |
Literature Information
PubMed PMID
|
19358280
|
Disease
|
Cervical carcinoma
|
Published Year
|
2009 |
Journal
|
International journal of cancer |
Title
|
Molecular variants of HPV-16 associated with cervical cancer in Indian population. |
Author
|
Pillai MR,Hariharan R,Babu JM,Lakshmi S,Chiplunkar SV,Patkar M,Tongaonkar H,Dinshaw K,Jayshree RS,Reddy BK,Siddiqui M,Roychoudury S,Saha B,Abraham P,Gnanamony M,Peedicayil A,Subhashini J,Ram TS,Dey B,Sharma C,Jain SK,Singh N |
Evidence
|
Twenty-nine alterations were seen in E7 region, with 12 being nonsynonymous. The most frequent being F57V (9%). L1 region showed 204 changes, of which 67 were nonsynonymous.
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