|
Mutation Information
|
Mutation Site
|
F53L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
PIs |
Literature Information
|
PubMed PMID
|
17500586
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2007 |
|
Journal
|
PLoS computational biology |
|
Title
|
HIV-1 subtype B protease and reverse transcriptase amino acid covariation. |
|
Author
|
Rhee SY,Liu TF,Holmes SP,Shafer RW |
|
Evidence
|
The mutations included in this analysis were the 22 positively associated mutations in Table 1 and 13 additional clinically relevant PI-resistance mutations (L10F, V32I, L33F, I47V, I50V/L, F53L, I54L/M, Q58E, L76V, V82T, and N88S).
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HIV Mutation Detail Information