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Mutation Information
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Mutation Site
|
F47R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
33374731
|
|
Published Year
|
2020 |
|
Journal
|
Cancers |
|
Title
|
High Risk α-HPV E6 Impairs Translesion Synthesis by Blocking POLη Induction. |
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Author
|
Wendel SO,Snow JA,Bastian T,Brown L,Hernandez C,Burghardt E,Kahn A,Murthy V,Neill D,Smith ZC,Ault K,Tawfik O,Wu C,Wallace NA |
|
Evidence
|
To address this gap, a well-defined dominant negative HPV 16 E6 mutant (HPV16 E6 F47R) was expressed exogenously in HeLa cells..
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HPV Mutation Detail Information