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Mutation Information
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Mutation Site
|
F456F |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E1 |
|
Amino acid_Mutation
|
T2232C |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
31341418
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2019 |
|
Journal
|
International journal of medical sciences |
|
Title
|
Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population. |
|
Author
|
Yao Y,Yan Z,Dai S,Li C,Yang L,Liu S,Zhang X,Shi L,Yao Y |
|
Evidence
|
In the sub-lineage analysis, the differences in the T933A (A23A), T1014G (D50E) and G2160A (R432R) mutations were statistically significant between the case and control groups for the A4 (As) sub-lineage (P<0.05), and the differences in the T2232C (F456F), G2337A (M491I) and A2547G (P561P) mutations were statistically significant between the case and control groups for the A1-A3 (EUR) sub-lineage (P<0.05).
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HPV Mutation Detail Information