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Mutation Information
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Mutation Site
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F39F |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Gp120 |
Literature Information
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PubMed PMID
|
31980614
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Published Year
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2020 |
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Journal
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Nature communications |
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Title
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Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. |
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Author
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Henderson R,Lu M,Zhou Y,Mu Z,Parks R,Han Q,Hsu AL,Carter E,Blanchard SC,Edwards RJ,Wiehe K,Saunders KO,Borgnia MJ,Bartesaghi A,Mothes W,Haynes BF,Acharya P,Munir Alam S |
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Evidence
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We also tested binding of the BG505 and mutant SOSIP Envs, in the presence and absence of sCD4, to a larger panel of V3 targeting MAbs, including 3074, 447-52D, and F39F.
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HIV Mutation Detail Information