Mutation Information
Mutation Site
|
F34I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vpr |
Literature Information
PubMed PMID
|
27343732
|
Published Year
|
2016 |
Journal
|
Virology |
Title
|
HIV-1 Vpr increases Env expression by preventing Env from endoplasmic reticulum-associated protein degradation (ERAD). |
Author
|
Zhang X,Zhou T,Frabutt DA,Zheng YH |
Evidence
|
To understand how Vpr could increase Env expression, we introduced 6 mutations into these regions of Vpr, which include A30L, F34I, W54R, Q65R, and H71R.
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