|
Mutation Information
|
Mutation Site
|
F32L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Tat |
Literature Information
|
PubMed PMID
|
17958917
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2007 |
|
Journal
|
Virology journal |
|
Title
|
Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort. |
|
Author
|
Sivakumaran H,Wang B,Gill MJ,Beckholdt B,Saksena NK,Harrich D |
|
Evidence
|
The low values for A5-4 and B3-2 are attributable to substitutions in the cysteine-rich domain of Tat (F32L and K28E, respectively), a critical region for transactivation and intramolecular bonding.
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HIV Mutation Detail Information