Mutation Information
Mutation Site
|
F271V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E2 |
Amino acid_Mutation
|
T3566G |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
HQ644251.1
|
Immune Escape
|
Y |
Country
|
China |
Literature Information
PubMed PMID
|
30008422
|
Disease
|
Cervical carcinoma
|
Published Year
|
2018 |
Journal
|
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
Title
|
The association of human papillomavirus type 16 E2 variations with cervical cancer in a Han Chinese population. |
Author
|
Dai S,Yao Y,Yan Z,Zhou Z,Shi L,Wang X,Sun L,Zhang R,Yao Y |
Evidence
|
Among the sixteen variations, C2860A (H35Q), A3181C (E142D), G3182A (A143T), and T3224A (L157I) were located in the transactivation domain; A3362G (N203D), C3377G (P208A), T3387C (I211T), C3516A (T254N), T3517C (T254N), A3538C (S261S) and T3566G (F271V) were located in the hinge region; and T3664C (Y303Y), T3694A (T313T), T3706C (S317S), G3778T (W341C), and T3805G (V350V) were located in the DNA binding domain.
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