HBV Mutation Detail Information

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Mutation Information

Mutation Site	F22L
Mutation Type	Amino acid level
Gene/Protein/Region Type	PreS2
Country	Vietnam

Literature Information

PubMed PMID	22720022
Disease	HBV-HCV-HIV coinfection
Published Year	2012
Journal	PloS one
Title	A multicentre molecular analysis of hepatitis B and blood-borne virus coinfections in Viet Nam.
Author	Dunford L,Carr MJ,Dean J,Nguyen LT,Ta Thi TH,Nguyen BT,Connell J,Coughlan S,Nguyen HT,Hall WW,Thi LA
Evidence	Analysis of the preS region demonstrated that a total of 5% of specimens had preS deletions (primarily identified in high risk individuals), 5.5% contained amino acid mutations in the start codon of the preS2 and 5.3% had an F22L mutation in the preS2, all of which have been significantly associated with the development of HCC

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation