HIV Mutation Detail Information

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Mutation Information

Mutation Site	F227L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	France;Italy

Literature Information

PubMed PMID	31976534
Disease	HIV infection/AIDS
Published Year	2020
Journal	The Journal of antimicrobial chemotherapy
Title	Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy.
Author	Soulie C,Santoro MM,Storto A,Abdi B,Charpentier C,Armenia D,Jary A,Forbici F,Bertoli A,Gennari W,Andreoni M,Mussini C,Antinori A,Perno CF,Calvez V,Ceccherini-Silberstein F,Descamps D,Marcelin AG
Evidence	The following mutations were considered as resistance mutations: V106A/M, V108I, Y188L, G190S, F227C/L/V, M230I/L, L234I, P236L, K103N + Y181C, K103N + P225H and K103N + L100I.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation