HIV Mutation Detail Information

> F227C Search Result

Mutation Information

Mutation Site	F227C
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	rilpivirine (RPV)

Literature Information

PubMed PMID	32701823
Disease	HIV infection/AIDS
Published Year	2020
Journal	Journal of acquired immune deficiency syndromes (1999)
Title	Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) From Dolutegravir (DTG)+F/TAF or DTG+F/Tenofovir Disoproxil Fumarate (TDF) in the Presence of Pre-existing NRTI Resistance.
Author	Acosta RK,Willkom M,Andreatta K,Liu H,Martin R,Parvangada A,Martin H,Collins S,White KL
Evidence	3 participants Rilpivirine resistance mutations (RPV-R) are L100I, K101E/P, E138A/G/K/Q/R, V179L, Y181C/I/V, Y188L, H221Y, F227C, and M230I/L in RT Acosta et al J Acquir Immune Defic Syndr Volume 85, Number 3, November 1, 2020.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation