HBV Mutation Detail Information

> F220C Search Result


Mutation Information
Mutation Site F220C
Mutation Type Amino acid level
Gene/Protein/Region Type S
Viral Reference AB697502; AB246345; JQ801515; AB246346; JQ801516; AB246339; AB900105; AB246342
Country Japan
Literature Information
PubMed PMID 30584239
Disease HBV infection
Published Year 2018
Journal Scientific reports
Title Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection.
Author Inuzuka T,Ueda Y,Arasawa S,Takeda H,Matsumoto T,Osaki Y,Uemoto S,Seno H,Marusawa H
Evidence Next, we also identified amino acid substitutions sL21S (n = 3) and sF220C (n = 4) in the MHC class II-restricted T-cell epitope region, which are reported to cause a complete loss of T-cell reactivity and anti-HBs production among individuals vaccinated against HBV in an ex vivo study

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation