HIV Mutation Detail Information

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Mutation Information
Mutation Site F185H
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Literature Information
PubMed PMID 19014951
Published Year 2009
Journal Journal of molecular biology
Title Defining the DNA substrate binding sites on HIV-1 integrase.
Author Dolan J,Chen A,Weber IT,Harrison RW,Leis J
Evidence The chimeras were assembled in a 3CSF185H background, an enzyme with four amino acid substitutions (C56S, C65S, C280S, and F185H) to improve solubility.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation