Mutation Information
Mutation Site
|
F185H |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Literature Information
PubMed PMID
|
19014951
|
Published Year
|
2009 |
Journal
|
Journal of molecular biology |
Title
|
Defining the DNA substrate binding sites on HIV-1 integrase. |
Author
|
Dolan J,Chen A,Weber IT,Harrison RW,Leis J |
Evidence
|
The chimeras were assembled in a 3CSF185H background, an enzyme with four amino acid substitutions (C56S, C65S, C280S, and F185H) to improve solubility.
|
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