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Mutation Information
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Mutation Site
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F185H |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
IN |
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Relevant Drug
|
mAb33 |
Literature Information
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PubMed PMID
|
16790058
|
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Published Year
|
2006 |
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Journal
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Retrovirology |
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Title
|
Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody. |
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Author
|
Ramcharan J,Colleluori DM,Merkel G,Andrake MD,Skalka AM |
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Evidence
|
The mutations that were introduced for this purpose encoded proteins with the following additional substitutions: 3CS/F185H, 3CS/F185K, 3CS/F185H/W131D/F139D, and 3CS/F185K/W131D/F139D.
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HIV Mutation Detail Information