HIV Mutation Detail Information

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Mutation Information
Mutation Site F185H
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Relevant Drug mAb33
Literature Information
PubMed PMID 16790058
Published Year 2006
Journal Retrovirology
Title Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody.
Author Ramcharan J,Colleluori DM,Merkel G,Andrake MD,Skalka AM
Evidence The mutations that were introduced for this purpose encoded proteins with the following additional substitutions: 3CS/F185H, 3CS/F185K, 3CS/F185H/W131D/F139D, and 3CS/F185K/W131D/F139D.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation