HBV Mutation Detail Information

> F161L Search Result

Mutation Information

Mutation Site	F161L
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	D

Literature Information

PubMed PMID	15328117
Disease	Chronic hepatitis B
Published Year	2004
Journal	Antimicrobial agents and chemotherapy
Title	Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine.
Author	Tenney DJ,Levine SM,Rose RE,Walsh AW,Weinheimer SP,Discotto L,Plym M,Pokornowski K,Yu CF,Angus P,Ayres A,Bartholomeusz A,Sievert W,Thompson G,Warner N,Locarnini S,Colonno RJ
Evidence	Substitution rtI169T causes an F161L substitution in HBV surface antigen (HBsAg), while substitution rtM250V is outside the HBsAg open reading frame.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation