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Mutation Information
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Mutation Site
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F160M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
|
rt.M184V+rt.F160M+rt.Q151M+rt.F116Y+rt.Y115F;rt.M184V+rt.Q182G+rt.F160M+rt.Q151M+rt.F116Y+rt.Y115F |
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Relevant Drug
|
entecavir (ETV);lamivudine (LAM);tenofovir alafenamide (TAF);islatravir (ISL);zidovudine (AZT) |
Literature Information
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PubMed PMID
|
32080249
|
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Published Year
|
2020 |
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Journal
|
Scientific reports |
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Title
|
Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. |
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Author
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Yasutake Y,Hattori SI,Tamura N,Matsuda K,Kohgo S,Maeda K,Mitsuya H |
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Evidence
|
Additionally, we experimentally simulated previously reported ETV/3TC resistance for HBV using HIVY115F/F116Y/Q151M with F160M/M184V (L180M/M204V in HBV RT) substituted.
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HIV Mutation Detail Information