HBV Mutation Detail Information

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Mutation Information
Mutation Site F134L
Mutation Type Amino acid level
Gene/Protein/Region Type S
Combined Mutation s.F134L+s.M133T+s.T131N
Genotype/Subtype C
Viral Reference AB033556; D00330
Country China
Literature Information
PubMed PMID 28600703
Disease Chronic hepatitis B
Published Year 2017
Journal Archives of virology
Title Prevalence of S gene mutations within the major hydrophilic region of hepatitis B virus in patients in Dongguan, southern China.
Author Li S,Xie M,Li W,Peng Q,Zhong B,Lu X,Ma Q
Evidence In genotype B strains, sY100C/Q129R/G145A, sY100C/E164G, sY100S/M133L, sM103I/T123A, sS114K/T116N/S132Y, sP120T/M133L, sP120S/K160N, sP120T/A157G, sP120Q/T126A, sK122I/P127T/G130N and sD144A/A157G were found (Fig. 1). In genotype C isolates, sY100C/Q101K, sY100C/I126N/M133T, sL104F/ G145R, sL109P/A128V/Q129K, sS114A/G145A, sG130K/A166G, sT131N/Q101K/I126S/M133T, sT131N/sM133T/F134L and sM133S/G145A and sT131N/M133S were found (Fig. 1).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation