Mutation Information
Mutation Site
|
F134L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
A |
Country
|
Irish |
Literature Information
PubMed PMID
|
18649329
|
Disease
|
Acute hepatitis B
|
Published Year
|
2008 |
Journal
|
Journal of medical virology |
Title
|
Molecular characterization of hepatitis B virus (HBV) isolates, including identification of a novel recombinant, in patients with acute HBV infection attending an Irish hospital. |
Author
|
Laoi BN,Crowley B |
Evidence
|
Variations within the S gene were identified in 6 isolates, including Gly145Ala, associated with vaccine immune escape, Asp144Glu, Ser143Leu and Phe134Leu, each associated with failure to detect HBsAg.
|
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