HIV Mutation Detail Information

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Mutation Information
Mutation Site F121Y
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Relevant Drug INSTIs
Country Turkey
Literature Information
PubMed PMID 27125365
Disease HIV infection/AIDS
Published Year 2016
Journal HIV clinical trials
Title Integrase Strand Transfer Inhibitors (INSTIs) Resistance Mutations in HIV-1 Infected Turkish Patients.
Author Sayan M,Gündüz A,Ersöz G,İnan A,Deveci A,Özgür G,Sargın F,Karagöz G,İnci A,İnan D,Ülçay A,Karaoğlan I,Kaya S,Kutlu SS,Süer K,Çağatay A,Akalın H
Evidence However, ARV-experienced patients had major resistance mutations associated with raltegravir and elvitegravir;the following results were generated:F121Y, Y143R, Q148R and E157Q (6/91 - 6.6%).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation