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Mutation Information
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Mutation Site
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F115S |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vif |
Literature Information
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PubMed PMID
|
16201018
|
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Clinical information
|
Yes
|
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Published Year
|
2005 |
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Journal
|
PLoS pathogens |
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Title
|
Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification. |
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Author
|
Simon V,Zennou V,Murray D,Huang Y,Ho DD,Bieniasz PD |
|
Evidence
|
In the presence of APOBEC3G, NL4-3 Vif harboring the mutations K22E, S32P, Y40H, E45G, F115S, G138R, or L150P failed to restore HIV-1 infectivity (Figure 4A).
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HIV Mutation Detail Information