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Mutation Information
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Mutation Site
|
F106Y |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
LMP1 |
Literature Information
|
PubMed PMID
|
19211641
|
|
Published Year
|
2009 |
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Journal
|
Haematologica |
|
Title
|
Comparative analysis of oncogenic properties and nuclear factor-kappaB activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes. |
|
Author
|
Faumont N,Chanut A,Benard A,Cogne N,Delsol G,Feuillard J,Meggetto F |
|
Evidence
|
LMP1 variants of Reed-Sternberg cell origin were often associated with increased mutation rate and with recurrent genetic events, such as del15bp associated with S to N replacement at codon 309, and four substitutions I85L, F106Y, I122L, and M129I.
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EBV Mutation Detail Information