|
Mutation Information
|
Mutation Site
|
F106Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
LMP1 |
|
Country
|
Russian |
Literature Information
|
PubMed PMID
|
18318128
|
|
Disease
|
Infectious mononucleosis;
Hodgkin lymphoma;
Non-Hodgkin lymphoma
|
|
Published Year
|
2008 |
|
Journal
|
Voprosy virusologii |
|
Title
|
[Mutations of the Epstein-Barr virus LMP1 gene mutations in Russian patients with lymphoid pathology and healthy individuals]. |
|
Author
|
Pavlish OA,Diduk SV,Smirnova KV,Shcherbak LN,Goncharova EV,Shalginskikh NA,Arkhipov VV,Kichigina MIu,Stepina VN,Belousova NV,Osmanov EA,Iakovleva LS,Gurtsevich VE |
|
Evidence
|
Among the point amino avid substitutions, the mutations S366T, F106Y, 185L, and E328Q associated with the enhanced transforming activity of a LMP1 molecule and its reduced cytotoxicity.
|
|
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EBV Mutation Detail Information