EBV Mutation Detail Information

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Mutation Information

Mutation Site	F105H
Mutation Type	Amino acid level
Gene/Protein/Region Type	BILF1

Literature Information

PubMed PMID	30647152
Published Year	2019
Journal	mBio
Title	Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation.
Author	Fares S,Spiess K,Olesen ETB,Zuo J,Jackson S,Kledal TN,Wills MR,Rosenkilde MM
Evidence	Moreover, both ZnPhe and ZnBip increased the F105H P268D double mutant EBV-BILF1 surface expression by ∼40% and 30%, respectively, at the highest concentration of the metal chelator (Fig. 5E and andF),F), whereas the effect on wt EBV-BILF1 expression was modest for ZnBip (∼15% at 10 µM) and absent for ZnPhe (Fig. 5E and andFF).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation