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Mutation Information
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Mutation Site
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E88A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vif |
Literature Information
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PubMed PMID
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24418540
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Published Year
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2014 |
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Journal
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Virology |
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Title
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Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis. |
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Author
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Matsui Y,Shindo K,Nagata K,Io K,Tada K,Iwai F,Kobayashi M,Kadowaki N,Harris RS,Takaori-Kondo A |
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Evidence
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In spreading infection, NL4-3 with Vif E88A/W89A mutation replicated comparably to wild-type virus in permissive CEM-SS cells, but not in multiple APOBEC3 expressing non-permissive CEM cells.
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HIV Mutation Detail Information