|
Mutation Information
|
Mutation Site
|
E77Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
C |
|
Country
|
Saudi Arabia |
Literature Information
|
PubMed PMID
|
30406036
|
|
Disease
|
HBV infection;
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2018 |
|
Journal
|
Frontiers in cellular and infection microbiology |
|
Title
|
The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease. |
|
Author
|
Al-Qahtani AA,Al-Anazi MR,Nazir N,Abdo AA,Sanai FM,Al-Hamoudi WK,Alswat KA,Al-Ashgar HI,Khan MQ,Albenmousa A,El-Shamy A,Alanazi SK,Dela Cruz D,Bohol MFF,Al-Ahdal MN |
|
Evidence
|
Two precore mutations, W28(*) and G29D, and six core mutations, F24Y, E64D, E77Q, A80I/T/V, L116I, and E180A were significantly associated with the development of cirrhosis and HCC.
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HBV Mutation Detail Information