Mutation Information
Mutation Site
|
E71A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
CA |
Viral Reference
|
K02013.1
|
Literature Information
PubMed PMID
|
24415937
|
Published Year
|
2014 |
Journal
|
PLoS pathogens |
Title
|
In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects. |
Author
|
Henning MS,Dubose BN,Burse MJ,Aiken C,Yamashita M |
Evidence
|
We depleted endogenous CPSF6 and infected the cells either with CA mutants that become dependent on cell division (E45A, Q63A/Q67A, A92E, G94D, and Q219A) or those that are impaired for infection but maintain cell cycle independence for infection (P38A, E71A, E128A/R132A and R143A).
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