Mutation Information
Mutation Site
|
E482K |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gp41 |
Literature Information
PubMed PMID
|
32098152
|
Published Year
|
2020 |
Journal
|
Viruses |
Title
|
Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5. |
Author
|
Roop JI,Cassidy NA,Dingens AS,Bloom JD,Overbaugh J |
Evidence
|
For example, the most highly enriched mutation following 293Trhm infection (N656Y) was enriched 34-fold relative to the wild-type residue, compared to a 12-fold enrichment for the most strongly selected mutation during 293Thu infection (E482K).
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