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Mutation Information
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Mutation Site
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E399G |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
Literature Information
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PubMed PMID
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33477685
|
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Published Year
|
2021 |
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Journal
|
Viruses |
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Title
|
Analysis and Molecular Determinants of HIV RNase H Cleavage Specificity at the PPT/U3 Junction. |
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Author
|
Álvarez M,Sapena-Ventura E,Luczkowiak J,Martín-Alonso S,Menéndez-Arias L |
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Evidence
|
However, the addition of E399G, T400A or T400S to N348I RT produced a slight increase in the amount of correctly processed PPT sequence, suggesting that those mutations could revert in part the RNase H cleavage window defect shown by N348I RT.
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HIV Mutation Detail Information