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Mutation Information
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Mutation Site
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E37D |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
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PubMed PMID
|
33503916
|
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Published Year
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2021 |
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Journal
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Molecules (Basel, Switzerland) |
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Title
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Structural Impacts of Drug-Resistance Mutations Appearing in HIV-2 Protease. |
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Author
|
Laville P,Petitjean M,Regad L |
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Evidence
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Indeed, we reported that the K7R, E37D, S43T, K45R, V47A, G48V, I50V, I50L, I54M, I54L, and V62A led atom shifts in the elbow and flap regions that could modify the flexibility and movement of the flap region important in the binding-pocket closing.
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HIV Mutation Detail Information