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HIV Mutation Detail Information

> E35S Search Result


Mutation Information
Mutation Site E35S
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Relevant Drug PIs
Literature Information
PubMed PMID 31409143
Published Year 2019
Journal Journal of enzyme inhibition and medicinal chemistry
Title Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease.
Author Maseko S,Padayachee E,Maphumulo S,Govender T,Sayed Y,Maguire G,Lin J,Naicker T,Baijnath S,Gerhardus KH
Evidence Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D G S mutant in the South African HIV-1 subtype C proteaseHerein, we report the effect of nine FDA approved protease inhibitor drugs against a new HIV-1 subtype C mutant protease, E35D G S.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation