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Mutation Information
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Mutation Site
|
E35D |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
PIs |
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Country
|
Brazil |
Literature Information
|
PubMed PMID
|
29844604
|
|
Disease
|
HIV-HBV coinfection;
HIV-HCV coinfection
|
|
Published Year
|
2018 |
|
Journal
|
Scientific reports |
|
Title
|
HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection. |
|
Author
|
Cantão NM,Fogaça de Almeida L,Rodrigo Wolf I,Oliveira Almeida R,Alves de Almeida Cruz A,Nunes C,Barbosa AN,Valente GT,de Moura Campos Pardini MI,Grotto RMT |
|
Evidence
|
Global sequence analysis showed that the most frequent amino acid substitutions in RT were S162C (29.4%), T200A (35.3%), M184V (32.3%), L214F (67.6%), I135T (55.9%), D177E (26.5%) and E122K (44.1%), and the most in PR were V15I (41.2%), M36I (38.2%) and E35D (23.5%).
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HIV Mutation Detail Information