HBV Mutation Detail Information

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Mutation Information

Mutation Site	E2G
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	B
Country	china guangzhou

Literature Information

PubMed PMID	32336003
Disease	Occult HBV infection
Published Year	2020
Journal	Journal of viral hepatitis
Title	Novel hepatitis B virus surface antigen mutations associated with occult genotype B hepatitis B virus infection affect HBsAg detection.
Author	Wang H,Wang M,Huang J,Xu R,Liao Q,Shan Z,Zheng Y,Rong X,Tang X,Li T,Wang W,Li C,Fu Y
Evidence	Notably, the E2G mutation had the most significant impact on the ratio of extracellular HBsAg (3.8% vs pHBV1.3B) and intracellular HBsAg (239.3% vs pHBV1.3B) (P < .05), and the fluorescence density of E2G mutant HBsAg was significantly higher than that of pHBV1.3B (P < .0001).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation