HIV Mutation Detail Information

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Mutation Information

Mutation Site	E28D
Mutation Type	Amino acid level
Gene/Protein/Region Type	CA
Combined Mutation	ca.K30E+ca.E28D
Genotype/Subtype	CRF08_BC
Viral Reference	K03455.1

Literature Information

PubMed PMID	30862755
Published Year	2019
Journal	mBio
Title	Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket.
Author	Craveur P,Gres AT,Kirby KA,Liu D,Hammond JA,Deng Y,Forli S,Goodsell DS,Williamson JR,Sarafianos SG,Olson AJ
Evidence	GenBank accession number AF308491 [https://www.ncbi.nlm.nih.gov/nuccore/AF308491]) show substitutions at those positions with K30R, E28D/K30E, and R18K, respectively (see Table S1 in the supplemental material).ubstitutions at those positions with K30R, E28D/K30E, and R18K, respectively (see Table S1 in the supplemental material).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation