HPV Mutation Detail Information

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Mutation Information
Mutation Site E25D
Mutation Type Amino acid level
Gene/Protein/Region Type E6
Genotype/Subtype HPV16
Viral Reference K02718.1
Country Japan
Literature Information
PubMed PMID 24236186
Disease High grade squamous intraepithelial lesion; Low grade squamous intraepithelial lesion; Cervical carcinoma
Published Year 2013
Journal PloS one
Title Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing.
Author Kukimoto I,Maehama T,Sekizuka T,Ogasawara Y,Kondo K,Kusumoto-Matsuo R,Mori S,Ishii Y,Takeuchi T,Yamaji T,Takeuchi F,Hanada K,Kuroda M
Evidence The nucleotide substitution in the E6 gene detected in sample 6 also leads to an aa change in the E6 protein, glutamic acid to aspartic acid at aa position 25.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation