Mutation Information
Mutation Site
|
E25D |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E6 |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
K02718.1
|
Country
|
Japan |
Literature Information
PubMed PMID
|
24236186
|
Disease
|
High grade squamous intraepithelial lesion;
Low grade squamous intraepithelial lesion;
Cervical carcinoma
|
Published Year
|
2013 |
Journal
|
PloS one |
Title
|
Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing. |
Author
|
Kukimoto I,Maehama T,Sekizuka T,Ogasawara Y,Kondo K,Kusumoto-Matsuo R,Mori S,Ishii Y,Takeuchi T,Yamaji T,Takeuchi F,Hanada K,Kuroda M |
Evidence
|
The nucleotide substitution in the E6 gene detected in sample 6 also leads to an aa change in the E6 protein, glutamic acid to aspartic acid at aa position 25.
|
|
|