EBV Mutation Detail Information

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Mutation Information

Mutation Site	E18G
Mutation Type	Amino acid level
Gene/Protein/Region Type	EBNA1
Viral Reference	V01555.2
Country	Western Australian

Literature Information

PubMed PMID	26849221
Disease	Multiple sclerosis
Published Year	2016
Journal	PloS one
Title	Identifying Patient-Specific Epstein-Barr Nuclear Antigen-1 Genetic Variation and Potential Autoreactive Targets Relevant to Multiple Sclerosis Pathogenesis.
Author	Tschochner M,Leary S,Cooper D,Strautins K,Chopra A,Clark H,Choo L,Dunn D,James I,Carroll WM,Kermode AG,Nolan D
Evidence	N-terminal sequence analysis showed high conservation and identified only three different variants: 19 samples demonstrated 100% sequence similarity with the N terminal sequence of the EBV reference strain B95-8, while 12 sequences matched the previously identified type 2 EBV strain AG876 which differs to B95-8 in the positions: Q16E, E18G, D24E, S27G and A85T.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation