HIV Mutation Detail Information

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Mutation Information

Mutation Site	E182V
Mutation Type	Amino acid level
Gene/Protein/Region Type	Env
Genotype/Subtype	B

Literature Information

PubMed PMID	32521274
Published Year	2020
Journal	Cell reports
Title	Slow Receptor Binding of the Noncytopathic HIV-2UC1 Envs Is Balanced by Long-Lived Activation State and Efficient Fusion Activity.
Author	Harris M,Ratnapriya S,Chov A,Cervera H,Block A,Gu C,Talledge N,Mansky LM,Sodroski J,Herschhorn A
Evidence	Nevertheless, introducing these changes (E182V, T266A, N337K, and V458W+Y459Q) into HIV-2UC1 did not significantly affect the general pattern of infectivity and sCD4 sensitivity (data not shown).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation