EBV Mutation Detail Information

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Mutation Information

Mutation Site	E176A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BILF1

Literature Information

PubMed PMID	30647152
Published Year	2019
Journal	mBio
Title	Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation.
Author	Fares S,Spiess K,Olesen ETB,Zuo J,Jackson S,Kledal TN,Wills MR,Rosenkilde MM
Evidence	The Δ17-N-term, K86A, E90A, C97A, P171A, C174A, R175A, E176A, and P178A mutants showed correlated signaling and MHC class I downregulation functions (Fig. 4E), where Δ17-N-term, K86A, P171A, R175A, E176A, and P178A mutants retained a wt-like signaling and MHC class I downregulation functions (Fig. 4E).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation