|
Mutation Information
|
Mutation Site
|
E164D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
16549970
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2006 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy. |
|
Author
|
Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL |
|
Evidence
|
All nine patients with the triple polymerase mutant (rtV173L/rtL180M/rtM204V) demonstrated 3TC resistance-associated changes in the envelope gene sE164D/sI195M.
|
|
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HBV Mutation Detail Information